Federation in Moderation

Everything in moderation

The presence of too many or too few centrosomes at mitosis can disrupt the timely formation of a bipolar spindle and may lead to aneuploidy and cancer. Strict control of centrosome duplication is therefore crucial. Centrosome duplication must occur once per cell cycle and the number of new centrioles made must be tightly controlled. The importance of protein degradation for the orderly progress...

Everything in Moderation 1 Everything in Moderation: A case for the balanced moderation of user-generated content on news sites

Moderation of user-generated content on news Web sites is an increasingly relevant and pertinent topic for online news entities. The quality and quantity of user-generated content can either help or hinder the number of audience members a news outlet receives. Considerations such as the amount of resources that can be given to moderation, the types of moderation, the types of usergenerated cont...

Everything in moderation, including vision.

SH3 domains: complexity in moderation.

The SH3 domain is perhaps the best-characterized member of the growing family of protein-interaction modules. By binding with moderate affinity and selectivity to proline-rich ligands, these domains play critical roles in a wide variety of biological processes ranging from regulation of enzymes by intramolecular interactions, increasing the local concentration or altering the subcellular locali...

Extremism drives out moderation

This article investigates the impact of the distribution of preferences on equilibrium behavior in conflicts that are modeled as all-pay auctions with identity-dependent externalities. In this context, we define centrists and radicals using a willingness-to-pay criterion that admits preferences more general than a simple ordering on the line. Through a series of examples, we show that substitut...